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For the term "occam".

Oh Fox!

Oh dear, it looks like Fox News took my script, and had a hollywood screenwriter make it more interesting:

http://www.myfoxcleveland.com/myfox/pages/News/Detail?contentId=1549984&version=8&locale=EN-US&layoutCode=VSTY&pageId=3.5.1

Mysterious Condition Finally Acknowledged!”, they say, which is a total misunderstanding. I’ll repeat what I said earlier:

The CDC is investigating why there seems to be an increase in the number of people reporting symptoms that look like DOP. Maybe there is an actual increase in cases due to some environmental cause (like pollution or fiberglass) or infectious agent (like MRSA), or it’s just a demographic shift with baby boomers hitting menopause, or maybe it’s an illusory increase, focussed by the media’s coverage of Morgellons, or maybe it’s magnified by the internet’s villagification of the world. Maybe a combination.

If you are new here, and really want to know what the medical community feels about Morgellons, read this link:

http://morgellonswatch.com/2006/09/22/doctors-patients/

Or this one, if you really want to get into details:

http://morgellonswatch.com/2006/10/29/morgellons-and-dermatologists/

Finally, I don’t want to pick on the people in the video, they are suffering enough. But really Fox, what was with that close up of the woman picking at her lip. The “white specks” which she claimed were emerging fibers looked just like dry skin peeling off her lip.

This is unprofessional scaremongering, which is HURTING PEOPLE. Fox should be ashamed. I only hope that the recent OJ reversal might prompt them to have a degree more oversight in the future.

[Addendum: Nov 23 2006]

I watched the video again, and one thing that grated was Professor Wymore again relating the story of how someone suggested that fibers might be getting under the skin by people injecting their skin with fibers in a saline solution mixed in a syringe. The way he says it suggests that’s the only explanation that has been offered by doctors.

Are thousands of people injecting themselves with fibers? Of course not! That is just ridiculous, and nobody is suggesting otherwise. And for anyone reading who thinks they have Morgellons, I’m not suggesting you did it either.

But might a few people be doing something like this? Is Wymore’s total rejection of this theory justified? It actually turns out that there are many well documented cases of people injecting themselves with things in order to get medical attention. People even inject their children with things, things much worse than fibers.

I’m not suggesting that Morgellons is caused by people injecting themselves with fibers! I’m just disappointed in Professor Wymore’s portrayal of a false dicotomy – for him it’s either a bizzare mind blowing disease new to science, or people are injecting fibers under their skin. Wymore takes the former, since he’s staked his reputation on it being true. Occam, if pressed, would take the latter, since it’s something known to happen. It explains a few cases, but don’t forget hot tubs, and menopause.

References:

http://www.local6.com/news/2770688/detail.html
Mom Accused Of Injecting Human Waste Into Daughter
Test Results Show IV Fluid Contained Substance Consistent With Fecal Matter

http://www.wboc.com/global/story.asp?s=3600148&ClientType=Printable
Mother Charged with Injecting Fecal matter into Toddler Son
McMullen is a former nurse at A.I. duPont Hospital for Children. She is accused of deliberately injecting fecal matter into her son, causing the toddler to be hospitalized numerous times.

http://www.postgradmed.com/issues/1999/12_99/kiester.htm
Occasionally, patients with Munchausen’s syndrome inject their knees to produce swelling, ingest agents to distort their laboratory findings, rub irritants on their skin to produce rashes, or wear splints or braces unnecessarily.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7802561&dopt=Abstract
A woman presented to our emergency center after self-injection of human chorionic gonadotropin in an attempt to gain admission to the hospital.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2102200&dopt=Abstract
The patient presented with bleeding from various sites; repeated subcutaneous emphysema of the face, orbit and upper chest; ulcers on the tongue, and dermatitis autogenica. The illness was confirmed to be factitious and self-induced when she was caught red-handed trying to inject air.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11903666&dopt=Abstract
We report herein a male patient displaying factitious disease of the breast due to injection of a high viscosity liquid plastic material. RESULTS: Establishment of the proper diagnosis was greatly delayed due to a lack of suspicion of this entity. Only direct confrontation of the patient with the biopsy results (lipogranulomatosis) led to a reluctant and then only partial admission of the self-induced nature of this patient’s illness.

Imagination

“How can thousands be experiencing the same DOP at the same time? That does not make sense.”

That’s a good question, because it’s a point often used by people who believe they have “Morgellons” to “prove” that it’s real.

Dismissing things because they “don’t make sense”, is an “argument from a lack of imagination“, which is somewhat ironic, since the one thing that Morgies do not seem to lack is imagination. They believe in several things that do not make sense, but they believe them because they seem to fit their view of the world.

So, how can thousands of people have the same condition? Obviously that’s the wrong question right there, as nearly every medical condition has thousands of sufferers.

No, the question being proposed is “how can thousands of individuals have the EXACT SAME DELUSION”?

This question actually has two complementary answers. 1) Easily, and 2) They don’t.

Let’s be clear about the delusion. A delusion is fixed false belief, held contrary to the evidence. The Morgellons delusion is not that people have sores, which they obviously do. It is not the fibers themselves, as there are clearly fibers everywhere. It is not the itching, since itching is a subjective experience. No, the Morgellons delusion is that the fibers are somehow connected to the sores and itching.

(1) How can people share this same delusion? Easily. People itch for a lot of reasons, some scratch a bit too much, forming blisters and sores. Sores are wet and sticky, they get debris in them, people think the debris (fibers, dirt, etc) is what is causing the sores, so they try to pick them out. Later they hear of Morgellons, and think “that’s it!”

(2) How can people share this same delusion? They don’t. They all have different delusions. They all have different experiences with their symptoms. Their physical illnesses are varied. Their theories are varied. Even the fibers are different. Compare Anne Dill, Greg Vigil, Stan Skoumal, Andrew Leitao, Mister X, Ever Hopeful, Cindy Casey. There’s a lot of variety there. They don’t all have the same thing.

People are ill. People are genuinely ill. They deserve compassion and they deserve treatment. Some of them have a lot of imagination. I just wish they could use that imagination to try to imagine the possibility that they might have been mistaken in some of their beliefs, and imagine the possibility that their lives might be a little better if they let go of Morgellons.

Whither Morgellons?

“Morgellons” is the name Mary Leitao chose for what she considered to be a mysterious new illness afflicting her son. Doctors told her it was just eczema, and that the fibers she found on his lip were just lint. But she was determined it must be a novel new disease that she personally had discovered, so she set up a foundation to publicise it. Eventually, via the internet, other people join her organization, the list of symptoms constituting “Morgellons” is expanded to include these new people. Eventually the list of symptoms becomes very broad, and encompasses just about any medical condition. Doctors reject “Morgellons”, since the symptoms are explained by other diseases, and are too varied and vague to constitute a working definition of a new disease.

But the “Foundation” continues on its mission of “raising awareness” of “this disease”. With lots of hard work they get some press coverage, then some local TV coverage, and then eventually some major TV coverage. Each time the story is the same. Some patients are presented who are obviously ill. Their doctors have told them Morgellons is not a real disease, and the fibers are just lint or hair. Wymore says it is a real disease. The CDC is investigating. The end.

viz.png
As you can see here, Morgellons was a short-lived phenomenon. The local media coverage spurred interest which faded away. The CNN story spurred some interested, but was limited by the audience. Finally two huge spikes surround the networks morning shows and the “Primetime” special, then nothing, it tails off to zero after the next two months.

So what’s going on? Was Morgellons just a product of a media desperate for news during the silly season? The MRF supplied them with an interesting sounding story, and they ran with it? Then what happened? Where did Morgellons go?

People are still sick, that’s for sure. People are still going to the doctors with excoriations, and with itching, and with fatigue, and with baggies of fibers. That’s not going to stop. There are a variety of reasons for that, and those reasons are not going away.

But “Morgellons” has gone away. It was a label someone decided to put on a bunch of symptoms without any evidence to indicate that anything unusual was happening, and contrary to the opinions of the entire medical community. A few people publicised it very well for a period of time. The media ran the story, but now they’ve “done that”, and there will be no more stories.

Save the inevitable CDC report on “insufficient evidence”, the inexplicable advocacy of Professor Wymore, and the interminable and sad believer’s theories on Morgellons discussion boards, Morgellons is over.

Morgellons is over, but people are still sick. They are probably more sick now than when the MRF started their media campaign. By popularizing “Morgellons” as an actual disease, it gave validity to those who disagree with their doctors, self diagnosed, and chose inappropriate treatments. Morgellons is over, but the damage is done.

Fibers on CNN

The recent CNN story on Morgellons (text version) was interesting as it focused on Randy Wymore’s examination of fibers, and actually showed his colleges removing fibers from a patient, and looking at them under a microscope.

In absence of any epidemiological studies, the only thing that makes the claims of Morgellons at all notable are the “fibers” that sufferers claim to have emerging from their skin. Now I’ve written quite a lot about this before, basically showing that fibers are everywhere, and that many of the photos of fibers shown can easily be identified as Kleenex, or clothing fibers.

The whole Morgellons case hinges around these fibers, which was the thing that originally got me interested – I think it’s high time that I get back to examining the fiber evidence, starting with the CNN video.

First of all, we have Dr Wymore in a thrift store, collecting fiber specimens from clothing with some scotch tape. The reporter then asks him if the fibers he found from Morgellons patients resemble clothing fibers. He responds “No, not at all, totally different”.

wymore-thrift-store.jpg
Here’s what Dr Wymore told me, on May 22, 2006:
You see, we do indeed find environmental contaminants in samples from Morgellons sufferers. Definitely cotton, likely from bandages and cellulose fibers, probably from tissue. But, we are not interested in the contaminants that are everywhere. We take the time to sort through the known fibers to examine in more detail the ones that look unusual.”

So what he’s saying here is that he ignores that fibers he can identify, and keeps looking until he finds fibers he cannot identify. I asked him if he did not think that in any sufficiently large sample of household fibers (laundry lint, for example), there would not be some fibers that he would be unable to identify – but so far he has declined to answer.

Later we have some footage of the Morgellons group examining patients, plucking fibers off them, and looking at them through a microscope. Dr Rhonda Casey, DO, points at a small blue fiber and says “That is definitely not a hair, the blue thing there”.

blue-fiber-on-skin.jpg

The fiber she points at looks exactly like standard tiny lint fiber. Probably blue cotton. She carefully take it off, and makes a slide.

This is what they saw”, the reporter says, and shows this picture:
microscope-blue-and-red.jpg
There’s a blue fiber in the middle that looks like a cotton fiber. For some reasons there are a bunch of other fibers that were not next to the blue fiber before. The clear ones in the middle look like cotton or paper, the large brown ones look like human hairs (at about 80 microns they are the correct size). The very dark lines look like the edge of a large air bubble.

We then see several other images, one of which is clearly a damaged human hair – you can even see the scales.
broken-hair-3-50.jpg

So what’s going on here? Randy Wymore is finding fibers that look different (to him) from clothing fibers. Well, notwithstanding that it’s almost inevitable that you will find unidentified fibers wherever you look, what might make ordinary fibers turn into the Morgellons fibers?

Let’s take a simplistic explanation. Say someone suffers from something that has symptoms of neurotic excoriations (they pick at their own skin, consciously or unconsciously). They are going to have many open lesions on their skin (forearms and faces being common areas). Now lesions are wet and sticky, so naturally they will have several tiny fibers stuck in them. Lesions also heal, so the tiny fibers become embedding in the new skin.

A few months later, just like a splinter, the fiber works its way to the surface of the skin. It may emerge at the original lesion site, or it may have migrated a few inches over. Is it surprising that a small blue piece of cotton that has spent many months under the skin, now looks nothing like clothing fibers plucked with scotch tape at the local thrift store?

That’s just a theory – but it’s a nice simple theory that explains things without introducing a mysterious pathogen. Occam’s Razor: “entities should not be multiplied beyond necessity”. Before claiming that because he cannot identify some fibers, then a new disease exists, Professor Wymore must explain how he has fully discounted the multitude of far simple explanations.

I’ll simplify this to two questions:

1) In any large sample of household fibers, will there not always be some that are unidentified?
2) If a clothing fiber were embedded in the skin for a long period of time, and then emerged, would you be able to identify it as a clothing fiber?